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PTBP1 promotes IRES-mediated translation of cyclin B1in cancer: PTBP1 promotes IRES-mediated translation of cyclin B1 in cancer

Cyclin B1 is an essential cyclin-dependent protein that involves in the G2/M transition. Multiple studies report that cyclin B1 is upregulated in cancers and promotes cancer progression. However, the mechanism of cyclin B1 upregulation remains unclear. Here we report that the 5′UTR of cyclin B1 mRNA...

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Detalles Bibliográficos
Autores principales: Fan, Xinyi, Zhao, Zitong, Ma, Liying, Huang, Xuanlin, Zhan, Qimin, Song, Yongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828304/
https://www.ncbi.nlm.nih.gov/pubmed/35643957
http://dx.doi.org/10.3724/abbs.2022046