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Alternative end-joining in BCR gene rearrangements and translocations: Alternative end-joining in BCR gene rearrangements and translocations

Programmed DNA double-strand breaks (DSBs) occur during antigen receptor gene recombination, namely V(D)J recombination in developing B lymphocytes and class switch recombination (CSR) in mature B cells. Repair of these DSBs by classical end-joining (c-NHEJ) enables the generation of diverse BCR rep...

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Detalles Bibliográficos
Autores principales: Bai, Wanyu, Zhao, Bo, Gu, Mingyu, Dong, Junchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828324/
https://www.ncbi.nlm.nih.gov/pubmed/35593472
http://dx.doi.org/10.3724/abbs.2022051