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NLRP3 inflammasome activation mechanism and its role in autoimmune liver disease: Role of NLRP3 inflammasome in autoimmune liver disease
The NLRP3 inflammasome is a multiprotein binding compound comprising NLRP3, connector protein ASC, and effector protein pro-caspase-1. When the NLRP3 inflammasome senses a danger signal from the host or pathogen, activated caspase-1 cleaves the precursors of interleukin (IL)-1β and IL-18 into mature...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828325/ https://www.ncbi.nlm.nih.gov/pubmed/36148948 http://dx.doi.org/10.3724/abbs.2022137 |