NLRP3 inflammasome activation mechanism and its role in autoimmune liver disease: Role of NLRP3 inflammasome in autoimmune liver disease

The NLRP3 inflammasome is a multiprotein binding compound comprising NLRP3, connector protein ASC, and effector protein pro-caspase-1. When the NLRP3 inflammasome senses a danger signal from the host or pathogen, activated caspase-1 cleaves the precursors of interleukin (IL)-1β and IL-18 into mature...

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Detalles Bibliográficos
Autores principales: Guan, Yanling, Gu, Yiyue, Li, Hao, Liang, Bo, Han, Chenchen, Zhang, Yu, Liu, Qian, Wei, Wei, Ma, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828325/
https://www.ncbi.nlm.nih.gov/pubmed/36148948
http://dx.doi.org/10.3724/abbs.2022137

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