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Positive allosteric regulation of PAC1-R up-regulatesPAC1-R and its specific ligand PACAP: Allosteric regulatory effects of PAC1-R

PAC1-R is a recognized preferential receptor for the neuropeptide of pituitary adenylate cyclase-activating polypeptide (PACAP), which mediates neuroprotective and nerve regenerative activities of PACAP. In this study, we found that in both PAC1R-CHO cells with high expression of PAC1R-eGFP and reti...

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Detalles Bibliográficos
Autores principales: Fan, Guangchun, Tao, Zhengxin, Chen, Shang, Zhang, Huahua, Yu, Rongjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828401/
https://www.ncbi.nlm.nih.gov/pubmed/35593471
http://dx.doi.org/10.3724/abbs.2022041