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Positive allosteric regulation of PAC1-R up-regulatesPAC1-R and its specific ligand PACAP: Allosteric regulatory effects of PAC1-R
PAC1-R is a recognized preferential receptor for the neuropeptide of pituitary adenylate cyclase-activating polypeptide (PACAP), which mediates neuroprotective and nerve regenerative activities of PACAP. In this study, we found that in both PAC1R-CHO cells with high expression of PAC1R-eGFP and reti...
Autores principales: | Fan, Guangchun, Tao, Zhengxin, Chen, Shang, Zhang, Huahua, Yu, Rongjie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828401/ https://www.ncbi.nlm.nih.gov/pubmed/35593471 http://dx.doi.org/10.3724/abbs.2022041 |
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