Novel hybrids of thiazolidinedione-1,3,4-oxadiazole derivatives: synthesis, molecular docking, MD simulations, ADMET study, in vitro, and in vivo anti-diabetic assessment

As compared to standard medicinal compounds, hybrid molecules that contain multiple biologically active functional groups have greater affinity and efficiency. Hence based on this concept, we predicted that a combination of thiazolidinediones and 1,3,4-oxadiazoles may enhance α-amylase and α-glucosi...

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Detalles Bibliográficos
Autores principales: Srinivasa, Mahendra Gowdru, Paithankar, Jagdish Gopal, Saheb Birangal, Sumit Rao, Pai, Aravinda, Pai, Vasudev, Deshpande, Shridhar N., Revanasiddappa, B. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828437/
https://www.ncbi.nlm.nih.gov/pubmed/36712616
http://dx.doi.org/10.1039/d2ra07247e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828437/
https://www.ncbi.nlm.nih.gov/pubmed/36712616
http://dx.doi.org/10.1039/d2ra07247e

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