Multivalent Benzamidine Molecules for Plasmin Inhibition: Effect of Valency and Linker Length

There is an emerging interest in utilizing synthetic multivalent inhibitors that comprise of multiple inhibitor moieties linked on a common scaffold to achieve strong and selective enzyme inhibition. As multivalent inhibition is impacted by valency and linker length, in this study, we explore the ef...

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Detalles Bibliográficos
Autores principales: Nallan Chakravarthula, Tanmaye, Zeng, Ziqian, Alves, Nathan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828467/
https://www.ncbi.nlm.nih.gov/pubmed/36111842
http://dx.doi.org/10.1002/cmdc.202200364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828467/
https://www.ncbi.nlm.nih.gov/pubmed/36111842
http://dx.doi.org/10.1002/cmdc.202200364

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