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Multivalent Benzamidine Molecules for Plasmin Inhibition: Effect of Valency and Linker Length
There is an emerging interest in utilizing synthetic multivalent inhibitors that comprise of multiple inhibitor moieties linked on a common scaffold to achieve strong and selective enzyme inhibition. As multivalent inhibition is impacted by valency and linker length, in this study, we explore the ef...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828467/ https://www.ncbi.nlm.nih.gov/pubmed/36111842 http://dx.doi.org/10.1002/cmdc.202200364 |