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Quantifying Reductive Amination in Nonenzymatic Amino Acid Synthesis

Amino acid biosynthesis initiates with the reductive amination of α‐ketoglutarate with ammonia to produce glutamate. However, the other α‐keto acids derived from the glyoxylate and Krebs cycles are converted into amino acids by transamination, rather than by reductive amination. Why is only one amin...

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Detalles Bibliográficos
Autores principales: Mayer, Robert J., Moran, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828492/
https://www.ncbi.nlm.nih.gov/pubmed/36121198
http://dx.doi.org/10.1002/anie.202212237