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Isoxazole Nucleosides as Building Blocks for a Plausible Proto‐RNA

The question of how RNA, as the principal carrier of genetic information evolved is fundamentally important for our understanding of the origin of life. The RNA molecule is far too complex to have formed in one evolutionary step, suggesting that ancestral proto‐RNAs (first ancestor of RNA) may have...

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Detalles Bibliográficos
Autores principales: Xu, Felix, Crisp, Antony, Schinkel, Thea, Dubini, Romeo C. A., Hübner, Sarah, Becker, Sidney, Schelter, Florian, Rovó, Petra, Carell, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828505/
https://www.ncbi.nlm.nih.gov/pubmed/36063071
http://dx.doi.org/10.1002/anie.202211945