Structure–Uptake Relationship Study of DABCYL Derivatives Linked to Cyclic Cell‐Penetrating Peptides for Live‐Cell Delivery of Synthetic Proteins

Modifying cyclic cell‐penetrating deca‐arginine (cR10) peptides with 4‐(4‐dimethylaminophenylazo)benzoic acid (DABCYL) improves the uptake efficiency of synthetic ubiquitin (Ub) cargoes into living cells. To probe the role of the DABCYL moiety, we performed time‐lapse microscopy and fluorescence lif...

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Detalles Bibliográficos
Autores principales: Saha, Abhishek, Mandal, Shaswati, Arafiles, Jan Vincent V., Gómez‐González, Jacobo, Hackenberger, Christian P. R., Brik, Ashraf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828537/
https://www.ncbi.nlm.nih.gov/pubmed/36004945
http://dx.doi.org/10.1002/anie.202207551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828537/
https://www.ncbi.nlm.nih.gov/pubmed/36004945
http://dx.doi.org/10.1002/anie.202207551

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