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Structure–Uptake Relationship Study of DABCYL Derivatives Linked to Cyclic Cell‐Penetrating Peptides for Live‐Cell Delivery of Synthetic Proteins
Modifying cyclic cell‐penetrating deca‐arginine (cR10) peptides with 4‐(4‐dimethylaminophenylazo)benzoic acid (DABCYL) improves the uptake efficiency of synthetic ubiquitin (Ub) cargoes into living cells. To probe the role of the DABCYL moiety, we performed time‐lapse microscopy and fluorescence lif...
Autores principales: | Saha, Abhishek, Mandal, Shaswati, Arafiles, Jan Vincent V., Gómez‐González, Jacobo, Hackenberger, Christian P. R., Brik, Ashraf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828537/ https://www.ncbi.nlm.nih.gov/pubmed/36004945 http://dx.doi.org/10.1002/anie.202207551 |
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