Antigiardial Activity of Novel Guanidine Compounds

From four focused compound libraries based on the known anticoccidial agent robenidine, 44 compounds total were synthesised and screened for antigiardial activity. All active compounds were counter‐screened for antibiotic and cytotoxic action. Of the analogues examined, 21 displayed IC(50)<5 μM,...

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Detalles Bibliográficos
Autores principales: Stevens, Andrew J., Abraham, Rebecca, Young, Kelly A., Russell, Cecilia C., McCluskey, Siobhann N., Baker, Jennifer R., Rusdi, Bertha, Page, Stephen W., O'Handley, Ryan, O'Dea, Mark, Abraham, Sam, McCluskey, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828538/
https://www.ncbi.nlm.nih.gov/pubmed/36085254
http://dx.doi.org/10.1002/cmdc.202200341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828538/
https://www.ncbi.nlm.nih.gov/pubmed/36085254
http://dx.doi.org/10.1002/cmdc.202200341

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