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Antigiardial Activity of Novel Guanidine Compounds
From four focused compound libraries based on the known anticoccidial agent robenidine, 44 compounds total were synthesised and screened for antigiardial activity. All active compounds were counter‐screened for antibiotic and cytotoxic action. Of the analogues examined, 21 displayed IC(50)<5 μM,...
Autores principales: | Stevens, Andrew J., Abraham, Rebecca, Young, Kelly A., Russell, Cecilia C., McCluskey, Siobhann N., Baker, Jennifer R., Rusdi, Bertha, Page, Stephen W., O'Handley, Ryan, O'Dea, Mark, Abraham, Sam, McCluskey, Adam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828538/ https://www.ncbi.nlm.nih.gov/pubmed/36085254 http://dx.doi.org/10.1002/cmdc.202200341 |
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