Superoxide Dismutase 1 Folding Stability as a Target for Molecular Tweezers in SOD1‐Related Amyotrophic Lateral Sclerosis

Protein misfolding and aggregation are hallmarks of many severe neurodegenerative diseases including Alzheimer's, Parkinson's and Huntington's disease. As a supramolecular ligand that binds to lysine and arginine residues, the molecular tweezer CLR01 was found to modify the aggregatio...

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Detalles Bibliográficos
Autores principales: Samanta, Nirnay, Ruiz‐Blanco, Yasser B., Fetahaj, Zamira, Gnutt, David, Lantz, Carter, Loo, Joseph A., Sanchez‐Garcia, Elsa, Ebbinghaus, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828543/
https://www.ncbi.nlm.nih.gov/pubmed/36083789
http://dx.doi.org/10.1002/cbic.202200396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828543/
https://www.ncbi.nlm.nih.gov/pubmed/36083789
http://dx.doi.org/10.1002/cbic.202200396

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