Super‐killer CTLs are generated by single gene deletion of Bach2

Bach2 codes for a transcriptional regulator exerting major influences on T cell‐mediated immune regulation. Effector CTLs derived from in vitro activation of murine CD8(+) T cells showed increased proliferative and cytolytic capacity in the absence of BACH2. Before activation, BACH2‐deficient spleni...

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Detalles Bibliográficos
Autores principales: Barton, Philippa R., Davenport, Alexander J., Hukelmann, Jens, Cantrell, Doreen A., Stinchcombe, Jane C., Richard, Arianne C., Griffiths, Gillian M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Adaptive immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828676/
https://www.ncbi.nlm.nih.gov/pubmed/36086884
http://dx.doi.org/10.1002/eji.202249797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828676/
https://www.ncbi.nlm.nih.gov/pubmed/36086884
http://dx.doi.org/10.1002/eji.202249797

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