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Tertiary lymphoid structures in desmoplastic melanoma have increased lymphocyte density, lymphocyte proliferation, and immune cross talk with tumor when compared to non-desmoplastic melanomas

Tertiary lymphoid structures (TLS) are ectopic lymphoid structures that can arise in human cancers and are associated with improved overall survival (OS) and response to immune checkpoint blockade (ICB) in several cancers, including non-desmoplastic metastatic melanoma (NDMM). Desmoplastic melanoma...

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Detalles Bibliográficos
Autores principales: Edmonds, Nicole L., Gradecki, Sarah E, Katyal, Priya, Lynch, Kevin T, Stowman, Anne M, Gru, Alejandro A, Engelhard, Victor H, Slingluff, Craig L, Mauldin, Ileana S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828737/
https://www.ncbi.nlm.nih.gov/pubmed/36632563
http://dx.doi.org/10.1080/2162402X.2022.2164476