An Extremely Stable Interprotein Tetrahedral Hg(Cys)(4) Core Forms in the Zinc Hook Domain of Rad50 Protein at Physiological pH

In nature, thiolate‐based systems are the primary targets of divalent mercury (Hg(II)) toxicity. The formation of Hg(Cys)( x ) cores in catalytic and structural protein centers mediates mercury's toxic effects and ultimately leads to cellular damage. Multiple studies have revealed distinct Hg(I...

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Detalles Bibliográficos
Autores principales: Łuczkowski, Marek, Padjasek, Michał, Ba Tran, Józef, Hemmingsen, Lars, Kerber, Olga, Habjanič, Jelena, Freisinger, Eva, Krężel, Artur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828754/
https://www.ncbi.nlm.nih.gov/pubmed/36222310
http://dx.doi.org/10.1002/chem.202202738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828754/
https://www.ncbi.nlm.nih.gov/pubmed/36222310
http://dx.doi.org/10.1002/chem.202202738

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