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An Extremely Stable Interprotein Tetrahedral Hg(Cys)(4) Core Forms in the Zinc Hook Domain of Rad50 Protein at Physiological pH
In nature, thiolate‐based systems are the primary targets of divalent mercury (Hg(II)) toxicity. The formation of Hg(Cys)( x ) cores in catalytic and structural protein centers mediates mercury's toxic effects and ultimately leads to cellular damage. Multiple studies have revealed distinct Hg(I...
Autores principales: | Łuczkowski, Marek, Padjasek, Michał, Ba Tran, Józef, Hemmingsen, Lars, Kerber, Olga, Habjanič, Jelena, Freisinger, Eva, Krężel, Artur |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828754/ https://www.ncbi.nlm.nih.gov/pubmed/36222310 http://dx.doi.org/10.1002/chem.202202738 |
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