Blocking connexin 43 hemichannel‐mediated ATP release reduces communication within and between tubular epithelial cells and medullary fibroblasts in a model of diabetic nephropathy

INTRODUCTION: Fibrosis of renal tubules is the final common pathway in diabetic nephropathy and develops in the face of tubular injury and fibroblast activation. Aberrant connexin 43 (Cx43) hemichannel activity has been linked to this damage under euglycaemic conditions, however, its role in glycaem...

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Detalles Bibliográficos
Autores principales: Williams, Bethany M., Cliff, Chelsy L., Demirel, Isak, Squires, Paul E., Hills, Claire E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
RESEARCH: BASIC SCIENCE SPECIAL ISSUE
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828766/
https://www.ncbi.nlm.nih.gov/pubmed/36256487
http://dx.doi.org/10.1111/dme.14963

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828766/
https://www.ncbi.nlm.nih.gov/pubmed/36256487
http://dx.doi.org/10.1111/dme.14963

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