Screening of rosmarinic acid from Salvia miltiorrhizae acting on the novel target TRPC1 based on the ‘homology modelling–virtual screening–molecular docking–affinity assay–activity evaluation’ method

CONTEXT: Salvia miltiorrhizae Bunge (Lamiaceae) is a traditional Chinese medicine (TCM) for the treatment of ‘thoracic obstruction’. Transient receptor potential canonical channel 1 (TRPC1) is a important target for myocardial injury treatment. OBJECTIVE: This work screens the active component actin...

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Detalles Bibliográficos
Autores principales: Quan, Wei, Wang, Yuan, Chen, Yu-han, Shao, Qing, Gong, Yang-ze, Hu, Jie-wen, Liu, Wei-hai, Wu, Zi-jun, Wang, Jie, Ma, Shan-bo, Li, Xiao-qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828776/
https://www.ncbi.nlm.nih.gov/pubmed/36604840
http://dx.doi.org/10.1080/13880209.2022.2160769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828776/
https://www.ncbi.nlm.nih.gov/pubmed/36604840
http://dx.doi.org/10.1080/13880209.2022.2160769

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