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RNA Chemical Labeling with Site‐Specific, Relative Quantification by Mass Spectrometry for the Structural Study of a Neomycin‐Sensing Riboswitch Aptamer Domain

High‐resolution mass spectrometry was used for the label‐free, direct localization and relative quantification of CMC(+)‐modifications of a neomycin‐sensing riboswitch aptamer domain in the absence and presence of the aminoglycoside ligands neomycin B, ribostamycin, and paromomycin. The chemical pro...

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Detalles Bibliográficos
Autores principales: Palasser, Michael, Breuker, Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828840/
https://www.ncbi.nlm.nih.gov/pubmed/36220343
http://dx.doi.org/10.1002/cplu.202200256