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Merkel cell polyomavirus small T antigen is a viral transcription activator that is essential for viral genome maintenance
Merkel cell polyomavirus (MCV) is a small DNA tumor virus that persists in human skin and causes Merkel cell carcinoma (MCC) in immunocompromised individuals. The multi-functional protein MCV small T (sT) activates viral DNA replication by stabilizing large T (LT) and promotes cell transformation th...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829177/ https://www.ncbi.nlm.nih.gov/pubmed/36574443 http://dx.doi.org/10.1371/journal.ppat.1011039 |