Merkel cell polyomavirus small T antigen is a viral transcription activator that is essential for viral genome maintenance

Merkel cell polyomavirus (MCV) is a small DNA tumor virus that persists in human skin and causes Merkel cell carcinoma (MCC) in immunocompromised individuals. The multi-functional protein MCV small T (sT) activates viral DNA replication by stabilizing large T (LT) and promotes cell transformation th...

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Detalles Bibliográficos
Autores principales: Rapchak, Kyle, Yagobian, Shiva D., Moore, Jackson, Khattri, Michelle, Shuda, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829177/
https://www.ncbi.nlm.nih.gov/pubmed/36574443
http://dx.doi.org/10.1371/journal.ppat.1011039

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