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Bayesian inference of multi-point macromolecular architecture mixtures at nanometre resolution

Gaussian spot fitting methods have significantly extended the spatial range where fluorescent microscopy can be used, with recent techniques approaching nanometre (nm) resolutions. However, small inter-fluorophore distances are systematically over-estimated for typical molecular scales. This bias ca...

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Detalles Bibliográficos
Autores principales: Embacher, Peter A., Germanova, Tsvetelina E., Roscioli, Emanuele, McAinsh, Andrew D., Burroughs, Nigel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829179/
https://www.ncbi.nlm.nih.gov/pubmed/36574448
http://dx.doi.org/10.1371/journal.pcbi.1010765