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Stress combined with loss of the Candida albicans SUMO protease Ulp2 triggers selection of aneuploidy via a two-step process

A delicate balance between genome stability and instability ensures genome integrity while generating genetic diversity, a critical step for evolution. Indeed, while excessive genome instability is harmful, moderated genome instability can drive adaptation to novel environments by maximising genetic...

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Detalles Bibliográficos
Autores principales: Rizzo, Marzia, Soisangwan, Natthapon, Vega-Estevez, Samuel, Price, Robert Jordan, Uyl, Chloe, Iracane, Elise, Shaw, Matt, Soetaert, Jan, Selmecki, Anna, Buscaino, Alessia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829183/
https://www.ncbi.nlm.nih.gov/pubmed/36574460
http://dx.doi.org/10.1371/journal.pgen.1010576