Early adversity promotes binge-like eating habits by remodeling a leptin-responsive lateral hypothalamus–brainstem pathway

Early-life trauma (ELT) is a risk factor for binge eating and obesity later in life, yet the neural circuits that underlie this association have not been addressed. Here, we show in mice that downregulation of the leptin receptor (Lepr) in the lateral hypothalamus (LH) and its effect on neural activ...

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Detalles Bibliográficos
Autores principales: Shin, Sora, You, In-Jee, Jeong, Minju, Bae, Yeeun, Wang, Xiao-Yun, Cawley, Mikel Leann, Han, Abraham, Lim, Byung Kook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829538/
https://www.ncbi.nlm.nih.gov/pubmed/36510113
http://dx.doi.org/10.1038/s41593-022-01208-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829538/
https://www.ncbi.nlm.nih.gov/pubmed/36510113
http://dx.doi.org/10.1038/s41593-022-01208-0

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