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Molecular homing and retention of muscle membrane stabilizing copolymers by non-invasive optical imaging in vivo

First-in-class membrane stabilizer Poloxamer 188 (P188) has been shown to confer membrane protection in an extensive range of clinical conditions; however, elements of the systemic distribution and localization of P188 at the organ, tissue, and muscle fiber levels in vivo have not yet been elucidate...

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Detalles Bibliográficos
Autores principales: Batti Angulski, Addeli Bez, Cohen, Houda, Kim, Mihee, Hahn, Dongwoo, Van Zee, Nicholas, Lodge, Timothy P., Hillmyer, Marc A., Hackel, Benjamin J., Bates, Frank S., Metzger, Joseph M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829555/
https://www.ncbi.nlm.nih.gov/pubmed/36654800
http://dx.doi.org/10.1016/j.omtm.2022.12.005