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Protein KIC5 is a novel regulator of artemisinin stress response in the malaria parasite Plasmodium falciparum

Artemisinin combination therapies (ACTs) have led to a significant decrease in Plasmodium falciparum malaria mortality. This progress is now threatened by emerging artemisinin resistance (ART-R) linked originally in SE Asia to polymorphisms in the Kelch propeller protein (K13) and more recently to s...

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Detalles Bibliográficos
Autores principales: Simmons, Caroline F., Gibbons, Justin, Zhang, Min, Oberstaller, Jenna, Pires, Camilla Valente, Casandra, Debora, Wang, Chengqi, Seyfang, Andreas, Otto, Thomas D., Rayner, Julian C., Adams, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829687/
https://www.ncbi.nlm.nih.gov/pubmed/36624300
http://dx.doi.org/10.1038/s41598-023-27417-6