Eliminating host-guest incompatibility via enzyme mining enables the high-temperature production of N-acetylglucosamine

The host-guest incompatibility between a production host and non-native enzymes has posed an arduous challenge for synthetic biology, particularly between mesophile-derived enzymes and a thermophilic chassis. In the present study, we develop a thermophilic enzyme mining strategy comprising an automa...

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Detalles Bibliográficos
Autores principales: Wu, Yutong, Liu, Jiongqin, Han, Xiao, Meng, Xuanlin, Li, Mengke, Wang, Jing, Xue, Hongsong, Yang, Yuhan, Xu, Ping, Tao, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829697/
https://www.ncbi.nlm.nih.gov/pubmed/36636338
http://dx.doi.org/10.1016/j.isci.2022.105774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829697/
https://www.ncbi.nlm.nih.gov/pubmed/36636338
http://dx.doi.org/10.1016/j.isci.2022.105774

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