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Zoledronic acid targets chemo-resistant polyploid giant cancer cells

Although polyploid giant cancer cells (PGCCs) are known as a key source of failure of current therapies, sufficient drugs to target these cells are not yet introduced. Considering the similarities of polyploid cells in regeneration and cancer, we hypothesized that zoledronic acid (ZA), an osteoclast...

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Detalles Bibliográficos
Autores principales: Adibi, Rezvan, Moein, Shiva, Gheisari, Yousof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829701/
https://www.ncbi.nlm.nih.gov/pubmed/36624105
http://dx.doi.org/10.1038/s41598-022-27090-1