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Site- and enantioselective cross-coupling of saturated N-heterocycles with carboxylic acids by cooperative Ni/photoredox catalysis

Site- and enantioselective cross-coupling of saturated N-heterocycles and carboxylic acids—two of the most abundant and versatile functionalities—to form pharmaceutically relevant α-acylated amine derivatives remains a major challenge in organic synthesis. Here, we report a general strategy for the...

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Detalles Bibliográficos
Autores principales: Shu, Xiaomin, Zhong, De, Huang, Qian, Huan, Leitao, Huo, Haohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829739/
https://www.ncbi.nlm.nih.gov/pubmed/36624097
http://dx.doi.org/10.1038/s41467-023-35800-0