Patient-specific identification of genome-wide DNA-methylation differences between intracranial and extracranial melanoma metastases

Melanomas frequently metastasize to distant organs and especially intracranial metastases still represent a major clinical challenge. Epigenetic reprogramming of intracranial metastases is thought to be involved in therapy failure, but so far only little is known about patient-specific DNA-methylati...

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Detalles Bibliográficos
Autores principales: Kraft, Theresa, Grützmann, Konrad, Meinhardt, Matthias, Meier, Friedegund, Westphal, Dana, Seifert, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829750/
https://www.ncbi.nlm.nih.gov/pubmed/36624125
http://dx.doi.org/10.1038/s41598-022-24940-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829750/
https://www.ncbi.nlm.nih.gov/pubmed/36624125
http://dx.doi.org/10.1038/s41598-022-24940-w

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