Continuous exposure to isoprenaline reduced myotube size by delaying myoblast differentiation and fusion through the NFAT-MEF2C signaling pathway

We aimed to explore whether superfluous sympathetic activity affects myoblast differentiation, fusion, and myofiber types using a continuous single-dose isoprenaline exposure model in vitro and to further confirm the role of distinct NFATs in ISO-mediated effects. Compared with delivery of single an...

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Detalles Bibliográficos
Autores principales: Yue, Jing, Xu, Wei, Xiang, Li, Chen, Shao-juan, Li, Xin-yuan, Yang, Qian, Zhang, Ruo-nan, Bao, Xin, Wang, Yan, Mbadhi, MagdaleenaNaemi, Liu, Yun, Yao, Lu-yuan, Chen, Long, Zhao, Xiao-ying, Hu, Chang-qing, Zhang, Jing-xuan, Zheng, Hong-tao, Wu, Yan, Chen, Shi-You, Li, Shan, Lv, Jing, Shi, Liu-liu, Tang, Jun-ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829891/
https://www.ncbi.nlm.nih.gov/pubmed/36624121
http://dx.doi.org/10.1038/s41598-022-22330-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829891/
https://www.ncbi.nlm.nih.gov/pubmed/36624121
http://dx.doi.org/10.1038/s41598-022-22330-w

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