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Jejunum-derived NF-κB reporter organoids as 3D models for the study of TNF-alpha-induced inflammation
Inflammation is an important process for epithelial barrier protection but when uncontrolled, it can also lead to tissue damage. The nuclear factor-kappa light chain enhancer of activated B cells (NF-κB) signaling pathway is particularly relevant in the intestine, as it seems to play a dual role. Wh...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829906/ https://www.ncbi.nlm.nih.gov/pubmed/36002565 http://dx.doi.org/10.1038/s41598-022-18556-3 |