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Amyloid-β in Alzheimer’s disease – front and centre after all?

The amyloid hypothesis, which proposes that accumulation of the peptide amyloid-β at synapses is the key driver of Alzheimer’s disease (AD) pathogenesis, has been the dominant idea in the field of Alzheimer’s research for nearly 30 years. Recently, however, serious doubts about its validity have eme...

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Detalles Bibliográficos
Autores principales: Weglinski, Caroline, Jeans, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829960/
https://www.ncbi.nlm.nih.gov/pubmed/36687366
http://dx.doi.org/10.1042/NS20220086