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Reversions to consensus are positively selected in HIV-1 and bias substitution rate estimates

Human immunodeficiency virus 1 (HIV-1) is a rapidly evolving virus able to evade host immunity through rapid adaptation during chronic infection. The HIV-1 group M has diversified since its zoonosis into several subtypes at a rate of the order of 10(−3) changes per site per year. This rate varies be...

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Detalles Bibliográficos
Autores principales: Druelle, Valentin, Neher, Richard A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829961/
https://www.ncbi.nlm.nih.gov/pubmed/36632482
http://dx.doi.org/10.1093/ve/veac118