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The effect of cladribine on immunoglobulin levels compared to B cell targeting therapies in multiple sclerosis

BACKGROUND: Cladribine is a useful therapeutic option in RRMS with moderate to high disease activity. Its oral formulation and tolerability make it a useful alternative to infusion therapies. Cladribine is known to deplete CD19(+) B lymphocytes, but its effect on immunoglobulin subsets is unclear. O...

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Detalles Bibliográficos
Autores principales: Lycett, Mitchell J, Lea, Rodney A, Maltby, Vicki E, Min, Myintzu, Lechner-Scott, Jeannette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830094/
https://www.ncbi.nlm.nih.gov/pubmed/36636583
http://dx.doi.org/10.1177/20552173221149688