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Bone-cartilage crosstalk informed by aging mouse bone transcriptomics and human osteoarthritis genome-wide association studies

Subchondral bone participates in crosstalk with articular cartilage to maintain joint homeostasis, and disruption of either tissue results in overall joint degeneration. Among the subchondral bone changes observed in osteoarthritis (OA), subchondral bone plate (SBP) thickening has a time-dependent r...

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Detalles Bibliográficos
Autores principales: Kaya, Serra, Bailey, Karsyn N., Schurman, Charles A., Evans, Daniel S., Alliston, Tamara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830153/
https://www.ncbi.nlm.nih.gov/pubmed/36636109
http://dx.doi.org/10.1016/j.bonr.2022.101647