LAG3 Regulates T Cell Activation and Plaque Infiltration in Atherosclerotic Mice

BACKGROUND: The immune checkpoint receptor lymphocyte-activation gene 3 (LAG3) is a new target for immune checkpoint blockade (ICB), but the effects of LAG3 on atherosclerosis are not known. OBJECTIVES: The aim of the study was to evaluate the role of LAG3 on plaque inflammation using murine hyperch...

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Detalles Bibliográficos
Autores principales: Mulholland, Megan, Kritikou, Eva, Katra, Pernilla, Nilsson, Jan, Björkbacka, Harry, Lichtman, Andrew H., Rodriguez, Annabelle, Engelbertsen, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830219/
https://www.ncbi.nlm.nih.gov/pubmed/36636446
http://dx.doi.org/10.1016/j.jaccao.2022.09.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830219/
https://www.ncbi.nlm.nih.gov/pubmed/36636446
http://dx.doi.org/10.1016/j.jaccao.2022.09.005

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