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Decitabine enhances the tumoricidal potential of TRAIL via the epigenetic regulation of death receptor 4 in gastric cancer

BACKGROUND: Deoxyribonucleic acid (DNA) methyltransferase inhibitors, such as decitabine, have made great advances in cancer therapy as combinational drugs. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) has an obvious anti-tumor effect; however, some gastric cancer (GC) cells are r...

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Detalles Bibliográficos
Autores principales: Li, Lin, Niu, Qian, Zhu, Yuanmin, Fan, Biao, Yang, Guibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830339/
https://www.ncbi.nlm.nih.gov/pubmed/36636077
http://dx.doi.org/10.21037/jgo-22-928