PRRX1 promotes colorectal cancer stemness and chemoresistance via the JAK2/STAT3 axis by targeting IL-6

BACKGROUND: Stemness acquirement is one of the hallmarks of cancer and the major reason for the chemoresistance and poor prognosis of colorectal cancer (CRC). Previous research has revealed the stimulatory role of paired related homeobox 1 (PRRX1) on CRC metastasis. However, the role of PRRX1 in ste...

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Detalles Bibliográficos
Autores principales: Zhong, Longzhu, Tan, Wanlin, Yang, Qianqiong, Zou, Zhaowei, Zhou, Rui, Huang, Yongsheng, Qiu, Zhenghua, Zheng, Kehong, Huang, Zonghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830354/
https://www.ncbi.nlm.nih.gov/pubmed/36636075
http://dx.doi.org/10.21037/jgo-22-1137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830354/
https://www.ncbi.nlm.nih.gov/pubmed/36636075
http://dx.doi.org/10.21037/jgo-22-1137

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