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A phase II randomized double blinded trial evaluating the efficacy of curcumin with pre-operative chemoradiation for rectal cancer

BACKGROUND: In vivo studies demonstrate that curcumin increases radioresponse of colorectal cancers. To demonstrate efficacy in humans, we performed a randomized double-blind study of locally advanced rectal cancer (LARC) patients receiving pre-operative chemoradiation therapy (CRT) ± curcumin. We u...

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Detalles Bibliográficos
Autores principales: Gunther, Jillian R., Chadha, Awalpreet S., Guha, Sushovan, Raju, Gottumukkala S., Maru, Dipen M., Munsell, Mark F., Jiang, Yan, Yang, Peiying, Felix, Edd, Clemons, Marilyn, Mathew, Geena George, Singh, Pankaj K., Skibber, John M., Rodriguez-Bigas, Miguel A., Chang, George J., Eng, Cathy, Delclos, Marc E., Crane, Christopher H., Das, Prajnan, Krishnan, Sunil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830363/
https://www.ncbi.nlm.nih.gov/pubmed/36636059
http://dx.doi.org/10.21037/jgo-22-259