Immodulin peptides influence musculoskeletal homeostasis by linking extracellular cues to macrophage and myoblast nuclear receptors

Immodulins are synthetic peptides derived from the C-terminal domains of insulin-like growth factor binding proteins (IGFBPs). Immodulins from the 3/5/6 (but not 1/2/4) IGFBP evolutionary clade transduce extracellular matrix (ECM) signals to RXR, NR4A1 and PPAR-alpha nuclear receptors (NRs) to stimu...

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Detalles Bibliográficos
Autor principal: Mascarenhas, Desmond D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830397/
https://www.ncbi.nlm.nih.gov/pubmed/36121116
http://dx.doi.org/10.4081/ejtm.2022.10695

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830397/
https://www.ncbi.nlm.nih.gov/pubmed/36121116
http://dx.doi.org/10.4081/ejtm.2022.10695

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