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Immodulin peptides influence musculoskeletal homeostasis by linking extracellular cues to macrophage and myoblast nuclear receptors
Immodulins are synthetic peptides derived from the C-terminal domains of insulin-like growth factor binding proteins (IGFBPs). Immodulins from the 3/5/6 (but not 1/2/4) IGFBP evolutionary clade transduce extracellular matrix (ECM) signals to RXR, NR4A1 and PPAR-alpha nuclear receptors (NRs) to stimu...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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PAGEPress Publications, Pavia, Italy
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830397/ https://www.ncbi.nlm.nih.gov/pubmed/36121116 http://dx.doi.org/10.4081/ejtm.2022.10695 |