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Therapeutic delivery of microRNA-125a-5p oligonucleotides improves recovery from myocardial ischemia/reperfusion injury in mice and swine

Rationale: Clinical application of mesenchymal stem cells (MSCs) and MSC-derived exosomes (MSC-Exos) to alleviate myocardial ischemia/reperfusion (I/R) injury is compromised by the low cell engraftment rate and uncontrolled exosomal content. As one of their active ingredients, single-component micro...

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Detalles Bibliográficos
Autores principales: Gao, Ling, Qiu, Fan, Cao, Hao, Li, Hao, Dai, Gonghua, Ma, Teng, Gong, Yanshan, Luo, Wei, Zhu, Dongling, Qiu, Zhixuan, Zhu, Ping, Chu, Shuguang, Yang, Huangtian, Liu, Zhongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830430/
https://www.ncbi.nlm.nih.gov/pubmed/36632217
http://dx.doi.org/10.7150/thno.73568