Sigma-1 receptor-regulated efferocytosis by infiltrating circulating macrophages/microglial cells protects against neuronal impairments and promotes functional recovery in cerebral ischemic stroke

Background: Efferocytosis of apoptotic neurons by macrophages is essential for the resolution of inflammation and for neuronal protection from secondary damage. It is known that alteration of the Sigma-1 receptor (Sig-1R) is involved in the pathological development of some neurological diseases, inc...

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Detalles Bibliográficos
Autores principales: Zhang, Gufang, Li, Qi, Tao, Weijie, Qin, Pingping, Chen, Jiali, Yang, Huicui, Chen, Jiaojiao, Liu, Hua, Dai, Qijun, Zhen, Xuechu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830433/
https://www.ncbi.nlm.nih.gov/pubmed/36632219
http://dx.doi.org/10.7150/thno.77088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830433/
https://www.ncbi.nlm.nih.gov/pubmed/36632219
http://dx.doi.org/10.7150/thno.77088

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