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Sesn2 Serves as a Regulator between Mitochondrial Unfolded Protein Response and Mitophagy in Intervertebral Disc Degeneration

Mitochondrial unfold protein response (UPR(mt)) can induce mitophagy to protect cell from unfold protein. However, how UPR(mt) induces mitophagy to protect cell is not yet clear. Herein, Sesn2 was considered to be a key molecule that communicated UPR(mt) and mitophagy in the intervertebral disc. Sil...

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Detalles Bibliográficos
Autores principales: Xu, Wen-Ning, Liu, Chun, Zheng, Huo-Liang, Xu, Hai-Xia, Yang, Run-Ze, Jiang, Sheng-Dan, Zhu, Li-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830501/
https://www.ncbi.nlm.nih.gov/pubmed/36632468
http://dx.doi.org/10.7150/ijbs.70211