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Inhibition of IGF2BP1 attenuates renal injury and inflammation by alleviating m6A modifications and E2F1/MIF pathway

Septic acute kidney injury (AKI) is characterized by inflammation. Pyroptosis often occurs during AKI and is associated with the development of septic AKI. This study found that induction of insulin-like growth factor 2 mRNA binding protein 1 (IGF2BP1) to a higher level can induce pyroptosis in rena...

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Detalles Bibliográficos
Autores principales: Mao, Yan, Jiang, Feng, Xu, Xue-Jiao, Zhou, Lan-Bo, Jin, Rui, Zhuang, Li-Li, Juan, Chen-Xia, Zhou, Guo-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830505/
https://www.ncbi.nlm.nih.gov/pubmed/36632449
http://dx.doi.org/10.7150/ijbs.78348